STRING 9.05 
  CHRNA1 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
CHRNA1
cholinergic receptor, nicotinic, alpha 1 (muscle); After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane (482 aa)
(Homo sapiens)
Predicted Functional Partners:
CHRND
cholinergic receptor, nicotinic, delta; After binding acetylcholine, the AChR responds by an ex [...] (517 aa)
    0.931
MAPK3
mitogen-activated protein kinase 3; Involved in both the initiation and regulation of meiosis, [...] (379 aa)
       0.899
MAPK1
mitogen-activated protein kinase 1; Involved in both the initiation and regulation of meiosis, [...] (360 aa)
       0.899
CHRNE
cholinergic receptor, nicotinic, epsilon; After binding acetylcholine, the AChR responds by an [...] (493 aa)
    0.829
CHRNG
cholinergic receptor, nicotinic, gamma; After binding acetylcholine, the AChR responds by an ex [...] (517 aa)
    0.769
IRF8
interferon regulatory factor 8; Specifically binds to the upstream regulatory region of type I [...] (426 aa)
       0.716
RAPSN
receptor-associated protein of the synapse; Thought to play some role in anchoring or stabilizi [...] (412 aa)
       0.661
AIRE
autoimmune regulator; Transcriptional regulator that binds to DNA as a dimer or as a tetramer, [...] (545 aa)
       0.657
ITGA7
integrin, alpha 7; Integrin alpha-7/beta-1 is the primary laminin receptor on skeletal myoblast [...] (1137 aa)
       0.621
CHRNB1
cholinergic receptor, nicotinic, beta 1 (muscle); After binding acetylcholine, the AChR respond [...] (501 aa)
     0.573
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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