STRING 9.05 
  GALC protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
GALC
galactosylceramidase; Hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Enzyme with very low activity responsible for the lysosomal catabolism of galactosylceramide, a major lipid in myelin, kidney and epithelial cells of small intestine and colon (685 aa)
(Homo sapiens)
Predicted Functional Partners:
ASAH1
N-acylsphingosine amidohydrolase (acid ceramidase) 1; Hydrolyzes the sphingolipid ceramide into [...] (411 aa)
      0.955
ARSA
arylsulfatase A; Hydrolyzes cerebroside sulfate (507 aa)
      0.953
GBA
glucosidase, beta; acid (includes glucosylceramidase) (536 aa)
      0.948
GAL3ST1
galactose-3-O-sulfotransferase 1; Catalyzes the sulfation of membrane glycolipids. Seems to pre [...] (423 aa)
      0.939
SMPD1
sphingomyelin phosphodiesterase 1, acid lysosomal; Converts sphingomyelin to ceramide. Also has [...] (631 aa)
      0.931
GLA
galactosidase, alpha (429 aa)
      0.927
UGCG
UDP-glucose ceramide glucosyltransferase; Catalyzes the first glycosylation step in glycosphing [...] (394 aa)
      0.914
CERK
ceramide kinase; Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phos [...] (537 aa)
      0.910
SGPP1
sphingosine-1-phosphate phosphatase 1; Has enzymatic activity against both sphingosine 1 phosph [...] (441 aa)
      0.904
ASAH2
N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2; Hydrolyzes the sphingolipid cera [...] (780 aa)
      0.904
 
  Views:                    
   Neighborhood  Fusion  Occurence  Coexpression  Experiments  Database  Textmining      Summary Network

 

Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:

additional (white) nodes

 Server load: low (12%)
Permalink