STRING 9.05 
  VWF protein (Homo sapiens) - STRING network view

This is the evidence view. Different line colors represent the types of evidence for the association.

Your Input:
von Willebrand factor; Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma (2813 aa)
(Homo sapiens)
Predicted Functional Partners:
glycoprotein Ib (platelet), alpha polypeptide; GP-Ib, a surface membrane protein of platelets, [...] (640 aa)
coagulation factor VIII, procoagulant component; Factor VIII, along with calcium and phospholip [...] (2351 aa)
ADAM metallopeptidase with thrombospondin type 1 motif, 13; Cleaves the vWF multimers in plasma [...] (1427 aa)
coagulation factor VII (serum prothrombin conversion accelerator); Initiates the extrinsic path [...] (466 aa)
vascular endothelial growth factor A; Growth factor active in angiogenesis, vasculogenesis and [...] (412 aa)
signal-regulatory protein alpha; Immunoglobulin-like cell surface receptor for CD47. Acts as do [...] (504 aa)
Putative uncharacterized protein IGLV3-21 (237 aa)
Ig kappa chain C region (240 aa)
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41); Integrin alph [...] (1039 aa)
GATA binding protein 2; Transcriptional activator which regulates endothelin-1 gene expression [...] (480 aa)
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
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additional (white) nodes

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