STRING 9.05 
  CYBA protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
CYBA
cytochrome b-245, alpha polypeptide; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide (195 aa)
(Homo sapiens)
Predicted Functional Partners:
NCF2
neutrophil cytosolic factor 2; NCF2, NCF1, and a membrane bound cytochrome b558 are required fo [...] (526 aa)
    0.997
NOX1
NADPH oxidase 1; NOH-1S is a voltage-gated proton channel that mediates the H(+) currents of re [...] (564 aa)
     0.997
NCF1
neutrophil cytosolic factor 1; May be required for activation of the latent NADPH oxidase (nece [...] (390 aa)
     0.996
NCF4
neutrophil cytosolic factor 4, 40kDa; Component of the NADPH-oxidase, a multicomponent enzyme s [...] (348 aa)
    0.993
CYBB
cytochrome b-245, beta polypeptide; Critical component of the membrane-bound oxidase of phagocy [...] (570 aa)
     0.990
RAC1
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1); Plasma [...] (211 aa)
     0.988
NOXO1
NADPH oxidase organizer 1; Constitutively potentiates the superoxide-generating activity of NOX [...] (376 aa)
     0.987
NOX4
NADPH oxidase 4; Constitutive NADPH oxidase which generates superoxide intracellularly upon for [...] (578 aa)
       0.955
NOX3
NADPH oxidase 3; NADPH oxidase which constitutively produces superoxide upon formation of a com [...] (568 aa)
      0.947
VCAM1
vascular cell adhesion molecule 1; Important in cell-cell recognition. Appears to function in l [...] (739 aa)
      0.933
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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