STRING 9.05 
  TRPV4 protein (Homo sapiens) - STRING network view

This is the evidence view. Different line colors represent the types of evidence for the association.

Your Input:
transient receptor potential cation channel, subfamily V, member 4; Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification. Also activated by low pH, citrate and phorbol esters. Increase of intracellular Ca(2+) potentiates currents. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism (871 aa)
(Homo sapiens)
Predicted Functional Partners:
calmodulin 1 (phosphorylase kinase, delta); Calmodulin mediates the control of a large number o [...] (149 aa)
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) (536 aa)
aquaporin 5; Forms a water-specific channel. Implicated in the generation of saliva, tears, and [...] (265 aa)
polycystic kidney disease 2 (autosomal dominant); Functions as a calcium permeable cation chann [...] (968 aa)
calmodulin 3 (phosphorylase kinase, delta) (149 aa)
calmodulin 2 (phosphorylase kinase, delta) (149 aa)
ubiquitin C (685 aa)
inositol 1,4,5-triphosphate receptor, type 3; Receptor for inositol 1,4,5-trisphosphate, a seco [...] (2671 aa)
itchy E3 ubiquitin protein ligase homolog (mouse); Essential component of a ubiquitin-editing p [...] (862 aa)
serum/glucocorticoid regulated kinase 1; Protein kinase that plays an important role in cellula [...] (526 aa)
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
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Co-expression Experiments Databases Textmining
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