STRING 9.05 
  CYP46A1 protein (Homo sapiens) - STRING network view

This is the evidence view. Different line colors represent the types of evidence for the association.

Your Input:
cytochrome P450, family 46, subfamily A, polypeptide 1; Involved in the turnover of cholesterol. It converts cholesterol into 24S-hydroxycholesterol and, to a lesser extent, 25-hydroxycholesterol (500 aa)
(Homo sapiens)
Predicted Functional Partners:
cholesterol 25-hydroxylase; Catalyzes the formation of 25-hydroxycholesterol from cholesterol, [...] (272 aa)
cytochrome P450, family 39, subfamily A, polypeptide 1; Involved in the bile acid metabolism. H [...] (469 aa)
cytochrome P450, family 27, subfamily A, polypeptide 1; Catalyzes the first step in the oxidati [...] (531 aa)
cytochrome P450, family 7, subfamily A, polypeptide 1 (504 aa)
24-dehydrocholesterol reductase; Catalyzes the reduction of the delta-24 double bond of sterol [...] (516 aa)
sterol O-acyltransferase 1; Catalyzes the formation of fatty acid-cholesterol esters. Plays a r [...] (550 aa)
7-dehydrocholesterol reductase; Production of cholesterol by reduction of C7-C8 double bond of [...] (475 aa)
carboxyl ester lipase (bile salt-stimulated lipase); Catalyzes fat and vitamin absorption. Acts [...] (756 aa)
lipase A, lysosomal acid, cholesterol esterase; Crucial for the intracellular hydrolysis of cho [...] (399 aa)
sterol O-acyltransferase 2; Plays a role in lipoprotein assembly and dietary cholesterol absorp [...] (522 aa)
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

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Co-expression Experiments Databases Textmining
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