STRING 9.05 
  PITX1 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
PITX1
paired-like homeodomain 1; May play a role in the development of anterior structures, and in particular, the brain and facies and in specifying the identity or structure of hindlimb (314 aa)
(Homo sapiens)
Predicted Functional Partners:
POMC
proopiomelanocortin; ACTH stimulates the adrenal glands to release cortisol (267 aa)
       0.893
RASAL1
RAS protein activator like 1 (GAP1 like); Probable inhibitory regulator of the Ras-cyclic AMP p [...] (804 aa)
       0.867
BMP4
bone morphogenetic protein 4; Induces cartilage and bone formation. Also act in mesoderm induct [...] (408 aa)
       0.867
TP53
tumor protein p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apo [...] (393 aa)
       0.825
GDF15
growth differentiation factor 15 (308 aa)
       0.809
PECR
peroxisomal trans-2-enoyl-CoA reductase; Participates in chain elongation of fatty acids. Has n [...] (303 aa)
       0.805
NEUROD1
neurogenic differentiation 1; Differentiation factor required for dendrite morphogenesis and ma [...] (356 aa)
      0.796
EGR1
early growth response 1; Transcriptional regulator. Recognizes and binds to the DNA sequence 5' [...] (543 aa)
      0.747
POU1F1
POU class 1 homeobox 1; Transcription factor involved in the specification of the lactotrope, s [...] (317 aa)
      0.746
NR5A1
nuclear receptor subfamily 5, group A, member 1; Transcriptional activator. Seems to be essenti [...] (461 aa)
      0.731
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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