STRING 9.05 
  ERBB3 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
ERBB3
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian); Binds and is activated by neuregulins and NTAK (1342 aa)
(Homo sapiens)
Predicted Functional Partners:
ERBB2
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene [...] (1255 aa)
    0.999
NRG1
neuregulin 1; Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recrui [...] (645 aa)
      0.999
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha); Binds to activated (phosphorylated) pr [...] (724 aa)
      0.999
NRG2
neuregulin 2; Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recrui [...] (858 aa)
     0.998
RNF41
ring finger protein 41; Acts as E3 ubiquitin-protein ligase and regulates the degradation of ta [...] (317 aa)
     0.998
EGF
epidermal growth factor (beta-urogastrone); EGF stimulates the growth of various epidermal and [...] (1207 aa)
     0.998
EGFR
epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avi [...] (1210 aa)
    0.997
PA2G4
proliferation-associated 2G4, 38kDa; May play a role in a ERBB3-regulated signal transduction p [...] (394 aa)
      0.993
GRB2
growth factor receptor-bound protein 2; Adapter protein that provides a critical link between c [...] (217 aa)
     0.992
SHC1
SHC (Src homology 2 domain containing) transforming protein 1; Signaling adapter that couples a [...] (584 aa)
     0.986
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
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additional (white) nodes

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