STRING 9.05 
  RAD51 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
RAD51
RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae); May participate in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Binds to single and double stranded DNA and exhibits DNA-dependent ATPase activity. Underwinds duplex DNA and forms helical nucleoprotein filaments (339 aa)
(Homo sapiens)
Predicted Functional Partners:
BRCA2
breast cancer 2, early onset; Involved in double-strand break repair and/or homologous recombin [...] (3418 aa)
    0.999
RAD52
RAD52 homolog (S. cerevisiae); Involved in double-stranded break repair. Plays a central role i [...] (418 aa)
    0.999
BRCA1
breast cancer 1, early onset; The BRCA1-BARD1 heterodimer coordinates a diverse range of cellul [...] (1863 aa)
    0.999
RAD51AP1
RAD51 associated protein 1; May participate in a common DNA damage response pathway associated [...] (352 aa)
     0.999
CHEK1
CHK1 checkpoint homolog (S. pombe); Required for checkpoint mediated cell cycle arrest in respo [...] (476 aa)
    0.999
TP53
tumor protein p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apo [...] (393 aa)
      0.999
MND1
meiotic nuclear divisions 1 homolog (S. cerevisiae); Required for proper homologous chromosome [...] (205 aa)
    0.998
BLM
Bloom syndrome, RecQ helicase-like; Participates in DNA replication and repair. Exhibits a magn [...] (1417 aa)
    0.998
ATM
ataxia telangiectasia mutated; Serine/threonine protein kinase which activates checkpoint signa [...] (3056 aa)
     0.998
SUMO1
SUMO1 pseudogene 3; Ubiquitin-like protein which can be covalently attached to target lysines a [...] (101 aa)
      0.996
 
  Views:                    
   Neighborhood  Fusion  Occurence  Coexpression  Experiments  Database  Textmining      Summary Network

 

Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:

additional (white) nodes

 Server load: low (22%)
Permalink