STRING 9.05 
  TPM1 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
TPM1
tropomyosin 1 (alpha); Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments (284 aa)
(Homo sapiens)
Predicted Functional Partners:
TNNT2
troponin T type 2 (cardiac); Troponin T is the tropomyosin-binding subunit of troponin, the thi [...] (295 aa)
     0.998
CALD1
caldesmon 1; Actin- and myosin-binding protein implicated in the regulation of actomyosin inter [...] (793 aa)
     0.996
TNNT1
troponin T type 1 (skeletal, slow); Troponin T is the tropomyosin-binding subunit of troponin, [...] (278 aa)
     0.994
TPM2
tropomyosin 2 (beta); Binds to actin filaments in muscle and non-muscle cells. Plays a central [...] (284 aa)
   0.986
VCL
vinculin; Involved in cell adhesion. May be involved in the attachment of the actin-based micro [...] (1134 aa)
     0.976
TTN
titin (33421 aa)
     0.975
TNNI3
troponin I type 3 (cardiac); Troponin I is the inhibitory subunit of troponin, the thin filamen [...] (210 aa)
      0.973
MYBPC3
myosin binding protein C, cardiac; Thick filament-associated protein located in the crossbridge [...] (1274 aa)
      0.973
LMOD1
leiomodin 1 (smooth muscle) (600 aa)
      0.965
DES
desmin; Desmin are class-III intermediate filaments found in muscle cells. In adult striated mu [...] (470 aa)
      0.963
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
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Co-expression Experiments Databases Textmining
 
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