STRING 9.05 
  NPC1 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
NPC1
Niemann-Pick disease, type C1; Involved in the intracellular trafficking of cholesterol. May play a role in vesicular trafficking in glia, a process that may be crucial for maintaining the structural and functional integrity of nerve terminals (1278 aa)
(Homo sapiens)
Predicted Functional Partners:
NPC2
Niemann-Pick disease, type C2; May be involved in the regulation of the lipid composition of sp [...] (151 aa)
      0.976
TMEM97
transmembrane protein 97 (176 aa)
       0.950
OSBPL5
oxysterol binding protein-like 5 (879 aa)
      0.922
UBC
ubiquitin C (685 aa)
       0.755
ETFA
electron-transfer-flavoprotein, alpha polypeptide; The electron transfer flavoprotein serves as [...] (333 aa)
       0.675
STARD3NL
STARD3 N-terminal like (234 aa)
       0.675
VPS4A
vacuolar protein sorting 4 homolog A (S. cerevisiae); Involved in late steps of the endosomal m [...] (437 aa)
      0.663
B4GALNT1
beta-1,4-N-acetyl-galactosaminyl transferase 1; Involved in the biosynthesis of gangliosides GM [...] (533 aa)
       0.657
TSPAN16
tetraspanin 16 (245 aa)
       0.657
STARD3
StAR-related lipid transfer (START) domain containing 3; Binds and transports cholesterol. Prom [...] (445 aa)
       0.651
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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