STRING 9.05 
  ERBB2 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
ERBB2
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian); Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Not activated by EGF, TGF- alpha and amphiregulin (1255 aa)
(Homo sapiens)
Predicted Functional Partners:
GRB2
growth factor receptor-bound protein 2; Adapter protein that provides a critical link between c [...] (217 aa)
     0.999
ERBB3
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian); Binds and is activated by ne [...] (1342 aa)
    0.999
EGFR
epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avi [...] (1210 aa)
    0.999
UBC
ubiquitin C (685 aa)
     0.999
GRB7
growth factor receptor-bound protein 7; Interacts with the cytoplasmic domain of the epidermal [...] (532 aa)
     0.999
SRC
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) (536 aa)
    0.999
HSP90AA1
heat shock protein 90kDa alpha (cytosolic), class A member 1; Molecular chaperone. Has ATPase a [...] (854 aa)
      0.999
ERBB2IP
erbb2 interacting protein; Acts as an adapter for the receptor ERBB2, in epithelia. By binding [...] (1371 aa)
     0.999
EGF
epidermal growth factor (beta-urogastrone); EGF stimulates the growth of various epidermal and [...] (1207 aa)
     0.998
SHC1
SHC (Src homology 2 domain containing) transforming protein 1; Signaling adapter that couples a [...] (584 aa)
     0.997
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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