STRING 9.05 
  POU2F1 protein (Homo sapiens) - STRING network view

This is the evidence view. Different line colors represent the types of evidence for the association.

Your Input:
POU class 2 homeobox 1; Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR (By similarity). In case of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby enabling the transcription of the viral immediate early genes (743 aa)
(Homo sapiens)
Predicted Functional Partners:
POU class 2 associating factor 1; Transcriptional coactivator that specifically associates with [...] (256 aa)
small nuclear RNA activating complex, polypeptide 4, 190kDa; Part of the SNAPc complex required [...] (1469 aa)
host cell factor C1 (VP16-accessory protein); Involved in control of the cell cycle. Also antag [...] (2035 aa)
breast cancer 1, early onset; The BRCA1-BARD1 heterodimer coordinates a diverse range of cellul [...] (1863 aa)
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor); Receptor for glucoco [...] (778 aa)
Sp1 transcription factor; Transcription factor that can activate or repress transcription in re [...] (785 aa)
TATA box binding protein; General transcription factor that functions at the core of the DNA-bi [...] (339 aa)
protein kinase, DNA-activated, catalytic polypeptide; Serine/threonine-protein kinase that acts [...] (4127 aa)
SRY (sex determining region Y)-box 2; Transcription factor that forms a trimeric complex with O [...] (317 aa)
X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rej [...] (732 aa)
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
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Co-expression Experiments Databases Textmining
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