STRING 9.05 
  ADRA2A protein (Homo sapiens) - STRING network view

This is the evidence view. Different line colors represent the types of evidence for the association.

Your Input:
adrenergic, alpha-2A-, receptor; Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is oxymetazoline > clonidine > epinephrine > norepinephrine > phenylephrine > dopamine > p-synephrine > p-tyramine > serotonin = p-octopamine. For antagonists, the rank order is yohimbine > phentolamine = mianserine > chlorpromazine = spiperone = prazosin > propanolol > alprenolol = pindolol (465 aa)
(Homo sapiens)
Predicted Functional Partners:
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2; Guanin [...] (355 aa)
adenylate cyclase 5; This is a membrane-bound, calcium-inhibitable adenylyl cyclase (1261 aa)
adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase (1091 aa)
adenylate cyclase 4; This is a membrane-bound, calmodulin-insensitive adenylyl cyclase (By simi [...] (1077 aa)
chemokine (C-C motif) ligand 19; May play a role not only in inflammatory and immunological res [...] (98 aa)
regulator of G-protein signaling 4; Inhibits signal transduction by increasing the GTPase activ [...] (302 aa)
melatonin receptor 1B; High affinity receptor for melatonin. Likely to mediates the reproductiv [...] (362 aa)
neuropeptide Y; NPY is implicated in the control of feeding and in secretion of gonadotrophin-r [...] (97 aa)
proopiomelanocortin; ACTH stimulates the adrenal glands to release cortisol (267 aa)
opioid receptor, mu 1; Inhibits neurotransmitter release by reducing calcium ion currents and i [...] (493 aa)
   Neighborhood  Fusion  Occurence  Coexpression  Experiments  Database  Textmining      Summary Network


Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
required confidence (score): interactors shown:
or custom value: or custom limit:

additional (white) nodes

 Server load: medium (68%)