STRING 9.05 
  ADRA2A protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
ADRA2A
adrenergic, alpha-2A-, receptor; Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is oxymetazoline > clonidine > epinephrine > norepinephrine > phenylephrine > dopamine > p-synephrine > p-tyramine > serotonin = p-octopamine. For antagonists, the rank order is yohimbine > phentolamine = mianserine > chlorpromazine = spiperone = prazosin > propanolol > alprenolol = pindolol (465 aa)
(Homo sapiens)
Predicted Functional Partners:
GNAI2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2; Guanin [...] (355 aa)
     0.964
ADCY5
adenylate cyclase 5; This is a membrane-bound, calcium-inhibitable adenylyl cyclase (1261 aa)
      0.942
ADCY2
adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase (1091 aa)
      0.938
ADCY4
adenylate cyclase 4; This is a membrane-bound, calmodulin-insensitive adenylyl cyclase (By simi [...] (1077 aa)
     0.927
CCL19
chemokine (C-C motif) ligand 19; May play a role not only in inflammatory and immunological res [...] (98 aa)
      0.919
RGS4
regulator of G-protein signaling 4; Inhibits signal transduction by increasing the GTPase activ [...] (302 aa)
      0.913
MTNR1B
melatonin receptor 1B; High affinity receptor for melatonin. Likely to mediates the reproductiv [...] (362 aa)
     0.913
NPY
neuropeptide Y; NPY is implicated in the control of feeding and in secretion of gonadotrophin-r [...] (97 aa)
      0.912
POMC
proopiomelanocortin; ACTH stimulates the adrenal glands to release cortisol (267 aa)
      0.910
OPRM1
opioid receptor, mu 1; Inhibits neurotransmitter release by reducing calcium ion currents and i [...] (493 aa)
     0.908
 
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