STRING 9.05 
  PTS protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
PTS
6-pyruvoyltetrahydropterin synthase; Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6- pyruvoyl tetrahydropterin (145 aa)
(Homo sapiens)
Predicted Functional Partners:
GCH1
GTP cyclohydrolase 1; Positively regulates nitric oxide synthesis in umbilical vein endothelial [...] (250 aa)
     0.993
PRKG2
protein kinase, cGMP-dependent, type II (762 aa)
     0.960
GCHFR
GTP cyclohydrolase I feedback regulator; Mediates tetrahydrobiopterin inhibition of GTP cyclohy [...] (84 aa)
      0.924
ALPP
alkaline phosphatase, placental (Regan isozyme) (535 aa)
      0.918
ALPL
alkaline phosphatase, liver/bone/kidney; This isozyme may play a role in skeletal mineralizatio [...] (524 aa)
      0.918
ALPPL2
alkaline phosphatase, placental-like 2 (532 aa)
      0.918
ALPI
alkaline phosphatase, intestinal (528 aa)
      0.900
EGFR
epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avi [...] (1210 aa)
       0.893
STAT1
signal transducer and activator of transcription 1, 91kDa; Signal transducer and activator of t [...] (750 aa)
       0.866
PTPN1
protein tyrosine phosphatase, non-receptor type 1; May play an important role in CKII- and p60c [...] (435 aa)
       0.839
 
  Views:                    
   Neighborhood  Fusion  Occurence  Coexpression  Experiments  Database  Textmining      Summary Network

 

Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:

additional (white) nodes

 Server load: low (25%)
Permalink