STRING 9.05 
  GJA1 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
GJA1
gap junction protein, alpha 1, 43kDa; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph (382 aa)
(Homo sapiens)
Predicted Functional Partners:
TJP1
tight junction protein 1 (zona occludens 1); The N-terminal may be involved in transducing a si [...] (1748 aa)
     0.997
SRC
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) (536 aa)
     0.996
PRKCA
protein kinase C, alpha; This is a calcium-activated, phospholipid-dependent, serine- and threo [...] (672 aa)
     0.994
MAPK7
mitogen-activated protein kinase 7; Plays a role in various cellular processes such as prolifer [...] (816 aa)
     0.993
PRKCG
protein kinase C, gamma; This is a calcium-activated, phospholipid-dependent, serine- and threo [...] (697 aa)
     0.987
UBC
ubiquitin C (685 aa)
      0.979
UBQLN4
ubiquilin 4 (601 aa)
      0.970
PRKG1
protein kinase, cGMP-dependent, type I; Phosphorylates PPP1R12A (686 aa)
      0.968
TUBA1A
tubulin, alpha 1a; Tubulin is the major constituent of microtubules. It binds two moles of GTP, [...] (451 aa)
      0.958
NOV
nephroblastoma overexpressed gene; Immediate-early protein likely to play a role in cell growth [...] (357 aa)
      0.945
 
  Views:                    
   Neighborhood  Fusion  Occurence  Coexpression  Experiments  Database  Textmining      Summary Network

 

Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:

additional (white) nodes

 Server load: low (33%)
Permalink