STRING 9.05 
  FLCN protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
FLCN
folliculin; May play a role in the pathogenesis of an uncommon form of kidney cancer through its association with an inherited disorder of the hair follicle (fibrofolliculomas). May be a tumor suppressor. May be involved in colorectal tumorigenesis. May be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways (579 aa)
(Homo sapiens)
Predicted Functional Partners:
FNIP1
folliculin interacting protein 1; May be involved in energy and/or nutrient sensing through the [...] (1166 aa)
      0.987
FNIP2
folliculin interacting protein 2; May be involved in energy and/or nutrient sensing through the [...] (1114 aa)
       0.952
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1; Phosphorylates specifically ribosomal protei [...] (525 aa)
       0.876
GPNMB
glycoprotein (transmembrane) nmb; Could be a melanogenic enzyme (By similarity) (572 aa)
       0.800
PRKAG1
protein kinase, AMP-activated, gamma 1 non-catalytic subunit; AMPK is responsible for the regul [...] (331 aa)
       0.718
PRKAA1
protein kinase, AMP-activated, alpha 1 catalytic subunit; Responsible for the regulation of fat [...] (574 aa)
       0.659
PRKAB1
protein kinase, AMP-activated, beta 1 non-catalytic subunit; AMPK is responsible for the regula [...] (270 aa)
       0.653
MTOR
mechanistic target of rapamycin (serine/threonine kinase); Kinase subunit of both mTORC1 and mT [...] (2549 aa)
       0.605
AGRP
agouti related protein homolog (mouse); Plays a role in weight homeostasis. May play a role in [...] (132 aa)
       0.571
MANF
mesencephalic astrocyte-derived neurotrophic factor; Selectively promotes the survival of dopam [...] (185 aa)
       0.551
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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