STRING 9.05 
  ERCC3 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
ERCC3
excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing); ATP-dependent 3'-5' DNA helicase, component of the core- TFIIH basal transcription factor, involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. Acts by opening DNA either around the RNA transcription start site or the DNA damage (782 aa)
(Homo sapiens)
Predicted Functional Partners:
ERCC2
excision repair cross-complementing rodent repair deficiency, complementation group 2; ATP-depe [...] (760 aa)
     0.999
CCNH
cyclin H; Regulates CDK7, the catalytic subunit of the CDK- activating kinase (CAK) enzymatic c [...] (323 aa)
    0.999
MNAT1
menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis); Stabilizes the cyclin H-CD [...] (309 aa)
    0.999
CDK7
cyclin-dependent kinase 7; Cyclin-dependent kinases (CDKs) are activated by the binding to a cy [...] (346 aa)
     0.999
GTF2H4
general transcription factor IIH, polypeptide 4, 52kDa (462 aa)
     0.999
GTF2H1
general transcription factor IIH, polypeptide 1, 62kDa; Component of the core-TFIIH basal trans [...] (548 aa)
    0.997
ERCC5
excision repair cross-complementing rodent repair deficiency, complementation group 5; Single-s [...] (1186 aa)
     0.997
GTF2H2
general transcription factor IIH, polypeptide 2, 44kDa; Component of the core-TFIIH basal trans [...] (395 aa)
     0.993
GTF2H3
general transcription factor IIH, polypeptide 3, 34kDa; Component of the core-TFIIH basal trans [...] (308 aa)
     0.992
GTF2E1
general transcription factor IIE, polypeptide 1, alpha 56kDa; Recruits TFIIH to the initiation [...] (439 aa)
    0.991
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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