STRING 9.05 
  GDF6 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
GDF6
growth differentiation factor 6; Required for normal formation of bones and joints in the limbs, skull, and axial skeleton. Play a key role in establishing boundaries between skeletal elements during development (By similarity) (455 aa)
(Homo sapiens)
Predicted Functional Partners:
NOG
noggin; Essential for cartilage morphogenesis and joint formation. Inhibitor of bone morphogene [...] (232 aa)
      0.975
BMPR2
bone morphogenetic protein receptor, type II (serine/threonine kinase); On ligand binding, form [...] (1038 aa)
     0.945
CHRD
chordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryon [...] (955 aa)
      0.866
PCNA
proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delt [...] (261 aa)
       0.809
AMHR2
anti-Mullerian hormone receptor, type II; On ligand binding, forms a receptor complex consistin [...] (573 aa)
      0.806
HES7
hairy and enhancer of split 7 (Drosophila); Transcriptional repressor. Represses transcription [...] (225 aa)
       0.788
BMPR1A
bone morphogenetic protein receptor, type IA; On ligand binding, forms a receptor complex consi [...] (532 aa)
      0.732
SMAD5
SMAD family member 5; Transcriptional modulator activated by BMP (bone morphogenetic proteins) [...] (464 aa)
      0.730
BMPR1B
bone morphogenetic protein receptor, type IB; On ligand binding, forms a receptor complex consi [...] (502 aa)
      0.723
RAX
retina and anterior neural fold homeobox; Plays a critical role in eye formation by regulating [...] (346 aa)
       0.653
 
  Views:                    
   Neighborhood  Fusion  Occurence  Coexpression  Experiments  Database  Textmining      Summary Network

 

Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:

additional (white) nodes

 Server load: low (19%)
Permalink