STRING 9.05 
  ZIC3 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
ZIC3
Zic family member 3 (odd-paired homolog, Drosophila); Probably functions as a transcription factor in the earliest stages of the left-right (LR) body axis formation (467 aa)
(Homo sapiens)
Predicted Functional Partners:
NOG
noggin; Essential for cartilage morphogenesis and joint formation. Inhibitor of bone morphogene [...] (232 aa)
       0.866
INHBE
inhibin, beta E; Inhibins and activins inhibit and activate, respectively, the secretion of fol [...] (350 aa)
       0.848
ACVR2B
activin A receptor, type IIB; On ligand binding, forms a receptor complex consisting of two typ [...] (512 aa)
       0.792
TDGF1
teratocarcinoma-derived growth factor 1; Could play a role in the determination of the epiblast [...] (188 aa)
      0.787
PASD1
PAS domain containing 1; May function as a transcription factor (773 aa)
       0.768
NODAL
nodal homolog (mouse); Essential for mesoderm formation and axial patterning during embryonic d [...] (347 aa)
       0.722
ESX1
ESX homeobox 1; May coordinately regulate cell cycle progression and transcription during sperm [...] (406 aa)
      0.681
GJA1
gap junction protein, alpha 1, 43kDa; One gap junction consists of a cluster of closely packed [...] (382 aa)
       0.677
LEFTY2
left-right determination factor 2; Required for left-right (L-R) asymmetry determination of org [...] (366 aa)
       0.677
LEFTY1
left-right determination factor 1; Required for left-right axis determination as a regulator of [...] (366 aa)
       0.675
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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