STRING 9.05 
  PRKAG2 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit; AMPK is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. Also regulates cholesterol synthesis via phosphorylation and inactivation of hydroxymethylglutaryl-CoA reductase and hormone- sensitive lipase. This is a regulatory subunit (569 aa)
(Homo sapiens)
Predicted Functional Partners:
PRKAB1
protein kinase, AMP-activated, beta 1 non-catalytic subunit; AMPK is responsible for the regula [...] (270 aa)
    0.994
PRKAG1
protein kinase, AMP-activated, gamma 1 non-catalytic subunit; AMPK is responsible for the regul [...] (331 aa)
    0.990
PRKAB2
protein kinase, AMP-activated, beta 2 non-catalytic subunit; AMPK is responsible for the regula [...] (272 aa)
     0.987
PRKAA1
protein kinase, AMP-activated, alpha 1 catalytic subunit; Responsible for the regulation of fat [...] (574 aa)
     0.984
PRKAA2
protein kinase, AMP-activated, alpha 2 catalytic subunit; Responsible for the regulation of fat [...] (552 aa)
     0.967
STK11
serine/threonine kinase 11; Essential role in G1 cell cycle arrest. Phosphorylates and activate [...] (433 aa)
      0.929
STRADA
STE20-related kinase adaptor alpha; Pseudokinase which, in complex with CAB39, binds to and act [...] (431 aa)
      0.910
RHEB
Ras homolog enriched in brain; Stimulates the phosphorylation of S6K1 and EIF4EBP1 through acti [...] (184 aa)
      0.906
PRKAG3
protein kinase, AMP-activated, gamma 3 non-catalytic subunit; AMPK is responsible for the regul [...] (489 aa)
     0.905
ACACB
acetyl-Coenzyme A carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or [...] (2458 aa)
      0.903
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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