STRING 9.05 
  UBR1 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
UBR1
ubiquitin protein ligase E3 component n-recognin 1; E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. May be involved in pancreatic homeostasis (1749 aa)
(Homo sapiens)
Predicted Functional Partners:
RECQL4
RecQ protein-like 4; DNA-dependent ATPase. May modulate chromosome segregation (1208 aa)
      0.831
UBC
ubiquitin C (685 aa)
      0.760
UBR5
ubiquitin protein ligase E3 component n-recognin 5; E3 ubiquitin-protein ligase which is a comp [...] (2799 aa)
       0.714
BSX
brain-specific homeobox; DNA binding protein that function as transcriptional activator. Is ess [...] (233 aa)
       0.679
FOS
FBJ murine osteosarcoma viral oncogene homolog; Nuclear phosphoprotein which forms a tight but [...] (380 aa)
      0.669
UBE2Z
ubiquitin-conjugating enzyme E2Z; Catalyzes the covalent attachment of ubiquitin to other prote [...] (354 aa)
       0.619
FAF2
Fas associated factor family member 2; May play a role in the translocation of terminally misfo [...] (445 aa)
      0.587
APEX1
APEX nuclease (multifunctional DNA repair enzyme) 1; Repairs oxidative DNA damages in vitro. Ma [...] (318 aa)
       0.571
TIRAP
toll-interleukin 1 receptor (TIR) domain containing adaptor protein; Adapter involved in the TL [...] (235 aa)
       0.569
UBA52
ubiquitin A-52 residue ribosomal protein fusion product 1; Protein modifier which can be covale [...] (128 aa)
       0.562
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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