STRING 9.05 
  CCR5 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
CCR5
chemokine (C-C motif) receptor 5; Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates (352 aa)
(Homo sapiens)
Predicted Functional Partners:
CCL5
chemokine (C-C motif) ligand 5; Chemoattractant for blood monocytes, memory T-helper cells and [...] (91 aa)
    0.999
CCL8
chemokine (C-C motif) ligand 8; Chemotactic factor that attracts monocytes, lymphocytes, basoph [...] (99 aa)
    0.997
CCL3
chemokine (C-C motif) ligand 3; Monokine with inflammatory and chemokinetic properties. Binds t [...] (92 aa)
    0.996
CCL2
chemokine (C-C motif) ligand 2; Chemotactic factor that attracts monocytes and basophils but no [...] (99 aa)
     0.996
CD4
CD4 molecule; Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regul [...] (458 aa)
      0.995
CCL3L1
chemokine (C-C motif) ligand 3-like 1; Chemotactic for lymphocytes and monocytes. Is a ligand f [...] (93 aa)
     0.995
CCL13
chemokine (C-C motif) ligand 13; Chemotactic factor that attracts monocytes, lymphocytes, basop [...] (98 aa)
    0.988
ADRBK1
adrenergic, beta, receptor kinase 1; Specifically phosphorylates the agonist-occupied form of t [...] (689 aa)
     0.988
JAK2
Janus kinase 2; Plays a role in leptin signaling and control of body weight (By similarity). Ty [...] (1132 aa)
     0.988
CXCL9
chemokine (C-X-C motif) ligand 9; Cytokine that affects the growth, movement, or activation sta [...] (125 aa)
     0.987
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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additional (white) nodes

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