STRING 9.05 
  LRP5 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
LRP5
low density lipoprotein receptor-related protein 5; Involved in the Wnt/beta catenin signaling pathway, probably by acting as a coreceptor together with Frizzled for Wnt (1615 aa)
(Homo sapiens)
Predicted Functional Partners:
AXIN1
axin 1; Controls dorsoventral patterning via two opposing effects; down-regulates beta-catenin [...] (862 aa)
     0.999
DKK1
dickkopf homolog 1 (Xenopus laevis); Inhibitor of Wnt signaling pathway (266 aa)
     0.997
WNT5A
wingless-type MMTV integration site family, member 5A; Ligand for members of the frizzled famil [...] (380 aa)
      0.988
CDH2
cadherin 2, type 1, N-cadherin (neuronal); Cadherins are calcium dependent cell adhesion protei [...] (906 aa)
      0.983
FZD4
frizzled homolog 4 (Drosophila); Receptor for Wnt proteins. Most of frizzled receptors are coup [...] (537 aa)
      0.976
FZD1
frizzled homolog 1 (Drosophila); Receptor for Wnt proteins. Most of frizzled receptors are coup [...] (647 aa)
      0.973
WNT1
wingless-type MMTV integration site family, member 1; Ligand for members of the frizzled family [...] (370 aa)
     0.972
CTNNB1
catenin (cadherin-associated protein), beta 1, 88kDa; Involved in the regulation of cell adhesi [...] (781 aa)
      0.962
FZD8
frizzled homolog 8 (Drosophila); Receptor for Wnt proteins. Most of frizzled receptors are coup [...] (694 aa)
     0.957
WNT7B
wingless-type MMTV integration site family, member 7B; Ligand for members of the frizzled famil [...] (349 aa)
      0.951
 
  Views:                    
   Neighborhood  Fusion  Occurence  Coexpression  Experiments  Database  Textmining      Summary Network

 

Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:

additional (white) nodes

 Server load: low (32%)
Permalink