STRING 9.05 
  CASR protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
CASR
calcium-sensing receptor; Senses changes in the extracellular concentration of calcium ions. The activity of this receptor is mediated by a G- protein that activates a phosphatidylinositol-calcium second messenger system (1078 aa)
(Homo sapiens)
Predicted Functional Partners:
EDN1
endothelin 1; Endothelins are endothelium-derived vasoconstrictor peptides (212 aa)
      0.981
FLNA
filamin A, alpha; Promotes orthogonal branching of actin filaments and links actin filaments to [...] (2647 aa)
      0.978
NPSR1
neuropeptide S receptor 1; May be active in signaling pathway in an autocrine or paracrine fash [...] (377 aa)
      0.976
PTH
parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing [...] (115 aa)
       0.965
GAST
gastrin; Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the [...] (101 aa)
      0.938
ADCY2
adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase (1091 aa)
      0.933
SST
somatostatin; Somatostatin inhibits the release of somatotropin (116 aa)
      0.929
RNF19A
ring finger protein 19A; E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin- [...] (838 aa)
      0.929
KNG1
kininogen 1; (1) Kininogens are inhibitors of thiol proteases; (2) HMW-kininogen plays an impor [...] (644 aa)
      0.928
GCG
glucagon; Glicentin may modulate gastric acid secretion and the gastro-pyloro-duodenal activity [...] (180 aa)
      0.926
 
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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
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Co-expression Experiments Databases Textmining
 
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