STRING 9.05 
  HPGD protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD); Prostaglandin inactivation. Contributes to the regulation of events that are under the control of prostaglandin levels. Catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4. Inhibits in vivo proliferation of colon cancer cells (266 aa)
(Homo sapiens)
Predicted Functional Partners:
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase); May have [...] (604 aa)
       0.917
IL1B
interleukin 1, beta; Produced by activated macrophages, IL-1 stimulates thymocyte proliferation [...] (269 aa)
       0.838
TGFBI
transforming growth factor, beta-induced, 68kDa; Binds to type I, II, and IV collagens. This ad [...] (683 aa)
       0.822
BIRC5
baculoviral IAP repeat-containing 5; Component of the chromosomal passenger complex (CPC), a co [...] (165 aa)
       0.805
HSD11B2
hydroxysteroid (11-beta) dehydrogenase 2; Catalyzes the conversion of cortisol to the inactive [...] (405 aa)
       0.722
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1; Catalyzes the dephosphorylation and conc [...] (537 aa)
       0.722
PTGES
prostaglandin E synthase (152 aa)
       0.609
SLCO2A1
solute carrier organic anion transporter family, member 2A1; May mediate the release of newly s [...] (643 aa)
       0.518
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase); May play [...] (599 aa)
       0.516
NR3C2
nuclear receptor subfamily 3, group C, member 2; Receptor for both mineralocorticoids (MC) such [...] (984 aa)
       0.506
 
  Views:                    
   Neighborhood  Fusion  Occurence  Coexpression  Experiments  Database  Textmining      Summary Network

 

Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
required confidence (score): interactors shown:
or custom value: or custom limit:

additional (white) nodes

 Server load: low (32%)
Permalink