STRING 9.05 
  NPM1 protein (Homo sapiens) - STRING network view

This is the evidence view. Different line colors represent the types of evidence for the association.

Your Input:
nucleophosmin (nucleolar phosphoprotein B23, numatrin); Involved in diverse cellular processes such as ribosome biogenesis, centrosome duplication, protein chaperoning, histone assembly, cell proliferation, and regulation of tumor suppressors TP53/p53 and ARF. Binds ribosome presumably to drive ribosome nuclear export. Associated with nucleolar ribonucleoprotein structures and bind single-stranded nucleic acids. Acts as a chaperonin for the core histones H3, H2B and H4 (294 aa)
(Homo sapiens)
Predicted Functional Partners:
nucleolin; Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found as [...] (710 aa)
cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4); Capable of inducing cell c [...] (173 aa)
ubiquitin C (685 aa)
tumor protein p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apo [...] (393 aa)
centromere protein A; Histone H3-like variant which exclusively replaces conventional H3 in the [...] (140 aa)
Holliday junction recognition protein; Centromeric protein that plays a central role in the inc [...] (748 aa)
NOP2/Sun domain family, member 2; RNA methyltransferase that methylates tRNAs, and possibly RNA [...] (767 aa)
SUMO1/sentrin/SMT3 specific peptidase 3; Protease that releases SUMO2 and SUMO3 monomers from s [...] (574 aa)
cyclin-dependent kinase 2; Involved in the control of the cell cycle. Interacts with cyclins A, [...] (298 aa)
small nucleolar RNA, C/D box 21; Required for rRNA maturation and formation of the 60S ribosoma [...] (297 aa)
   Neighborhood  Fusion  Occurence  Coexpression  Experiments  Database  Textmining      Summary Network


Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
required confidence (score): interactors shown:
or custom value: or custom limit:

additional (white) nodes

 Server load: medium (64%)