STRING 9.05 
  TNFRSF11B protein (Homo sapiens) - STRING network view

This is the evidence view. Different line colors represent the types of evidence for the association.

Your Input:
tumor necrosis factor receptor superfamily, member 11b; Acts as decoy receptor for RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local RANKL/OPG ratio. May also play a role in preventing arterial calcification. May act as decoy receptor for TRAIL and protect against apoptosis. TRAIL binding blocks the inhibition of osteoclastogenesis (401 aa)
(Homo sapiens)
Predicted Functional Partners:
tumor necrosis factor (ligand) superfamily, member 11; Cytokine that binds to TNFRSF11B/OPG and [...] (317 aa)
tumor necrosis factor (ligand) superfamily, member 10; Cytokine that binds to TNFRSF10A/TRAILR1 [...] (281 aa)
transforming growth factor, beta 1; Multifunctional protein that controls proliferation, differ [...] (390 aa)
interleukin 18 (interferon-gamma-inducing factor); Augments natural killer cell activity in spl [...] (193 aa)
interleukin 17A; Induces stromal cells to produce proinflammatory and hematopoietic cytokines. [...] (155 aa)
peroxisome proliferator-activated receptor gamma; Receptor that binds peroxisome proliferators [...] (505 aa)
coagulation factor II (thrombin); Thrombin, which cleaves bonds after Arg and Lys, converts fib [...] (622 aa)
prolactin; Prolactin acts primarily on the mammary gland by promoting lactation (227 aa)
insulin-like growth factor 1 receptor; This receptor binds insulin-like growth factor 1 (IGF1) [...] (1367 aa)
bone morphogenetic protein receptor, type II (serine/threonine kinase); On ligand binding, form [...] (1038 aa)
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