STRING 9.05 
  CDK5 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
CDK5
cyclin-dependent kinase 5; Probably involved in the control of the cell cycle. Interacts with D1 and D3-type G1 cyclins. Can phosphorylate histone H1, tau, MAP2 and NF-H and NF-M. Also interacts with p35 which activates the kinase (292 aa)
(Homo sapiens)
Predicted Functional Partners:
CDK5R1
cyclin-dependent kinase 5, regulatory subunit 1 (p35); p35 is a neuron specific activator of CD [...] (307 aa)
     0.999
NDEL1
nudE nuclear distribution gene E homolog (A. nidulans)-like 1; Facilitates the polymerization o [...] (345 aa)
     0.997
CDK5R2
cyclin-dependent kinase 5, regulatory subunit 2 (p39); Activator of CDK5/TPKII (367 aa)
     0.996
PPP1R1B
protein phosphatase 1, regulatory (inhibitor) subunit 1B; Inhibitor of protein-phosphatase 1 (204 aa)
     0.996
MAPT
microtubule-associated protein tau; Promotes microtubule assembly and stability, and might be i [...] (776 aa)
      0.996
CABLES1
Cdk5 and Abl enzyme substrate 1; Cyclin-dependent kinase binding protein. Enhances cyclin-depen [...] (633 aa)
     0.991
NES
nestin; May play a role in the trafficking and distribution of IF proteins and potentially othe [...] (1621 aa)
      0.990
DPYSL2
dihydropyrimidinase-like 2; Necessary for signaling by class 3 semaphorins and subsequent remod [...] (572 aa)
      0.987
CRMP1
collapsin response mediator protein 1; Necessary for signaling by class 3 semaphorins and subse [...] (686 aa)
      0.985
ENSG00000235320
microtubule-associated protein tau isoform 5 (776 aa)
      0.980
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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