STRING 9.05 
  PHOX2A protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
PHOX2A
paired-like homeobox 2a; May be involved in regulating the specificity of expression of the catecholamine biosynthetic genes. Acts as a transcription activator/factor. Could maintain the noradrenergic phenotype (284 aa)
(Homo sapiens)
Predicted Functional Partners:
BMP2
bone morphogenetic protein 2; Induces cartilage and bone formation (396 aa)
       0.843
CREB1
cAMP responsive element binding protein 1; This protein binds the cAMP response element (CRE), [...] (341 aa)
       0.829
FOS
FBJ murine osteosarcoma viral oncogene homolog; Nuclear phosphoprotein which forms a tight but [...] (380 aa)
       0.817
CDKN1B
cyclin-dependent kinase inhibitor 1B (p27, Kip1); Important regulator of cell cycle progression [...] (198 aa)
       0.805
EYA1
eyes absent homolog 1 (Drosophila); Tyrosine phosphatase that specifically dephosphorylates 'Ty [...] (592 aa)
       0.800
KIF21A
kinesin family member 21A; Microtubule-binding motor protein probably involved in neuronal axon [...] (1661 aa)
       0.798
HAND2
heart and neural crest derivatives expressed 2; Essential for cardiac morphogenesis, particular [...] (217 aa)
      0.798
HCN2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2; Hyperpolarization-acti [...] (889 aa)
       0.778
HCN4
hyperpolarization activated cyclic nucleotide-gated potassium channel 4; Hyperpolarization-acti [...] (1203 aa)
       0.768
CDC42EP5
CDC42 effector protein (Rho GTPase binding) 5; Probably involved in the organization of the act [...] (148 aa)
       0.744
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
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Co-expression Experiments Databases Textmining
 
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