STRING 9.05 
  SPRED1 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
SPRED1
sprouty-related, EVH1 domain containing 1; Tyrosine kinase substrate that inhibits growth-factor- mediated activation of MAP kinase. Negatively regulates hematopoiesis of bone marrow (By similarity) (444 aa)
(Homo sapiens)
Predicted Functional Partners:
TESK1
testis-specific kinase 1; Dual specificity protein kinase activity catalyzing autophosphorylati [...] (626 aa)
      0.930
HRAS
v-Ha-ras Harvey rat sarcoma viral oncogene homolog; Ras proteins bind GDP/GTP and possess intri [...] (189 aa)
      0.913
TAOK1
TAO kinase 1; Phosphorylates MKK3 (By similarity). Activates the p38 MAP kinase pathway through [...] (1001 aa)
       0.826
KIT
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; This is the receptor for stem ce [...] (976 aa)
      0.751
CRTC1
CREB regulated transcription coactivator 1; Transcriptional coactivator for CREB1 which activat [...] (650 aa)
       0.714
ADCY2
adenylate cyclase 2 (brain); This is a membrane-bound, calmodulin-insensitive adenylyl cyclase (1091 aa)
       0.653
UBC
ubiquitin C (685 aa)
       0.645
EGFL7
EGF-like-domain, multiple 7; Regulates vascular tubulogenesis in vivo. Inhibits platelet-derive [...] (273 aa)
       0.607
PPP1CA
protein phosphatase 1, catalytic subunit, alpha isoform; Protein phosphatase 1 (PP1) is essenti [...] (341 aa)
       0.556
RAF1
v-raf-1 murine leukemia viral oncogene homolog 1; Involved in the transduction of mitogenic sig [...] (648 aa)
       0.501
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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