STRING 9.05 
  NOD2 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
NOD2
nucleotide-binding oligomerization domain containing 2; Induces NF-kappa-B via RICK (CARDIAK, RIP2) and IKK- gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS) (1040 aa)
(Homo sapiens)
Predicted Functional Partners:
RIPK2
receptor-interacting serine-threonine kinase 2; Activates pro-caspase-1 and pro-caspase-8. Pote [...] (540 aa)
     0.999
CASP1
caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase); Thiol protea [...] (404 aa)
      0.988
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma; Regulatory subunit [...] (487 aa)
     0.968
ATG16L1
ATG16 autophagy related 16-like 1 (S. cerevisiae); Plays an essential role in autophagy (By sim [...] (607 aa)
       0.953
RIPK1
receptor (TNFRSF)-interacting serine-threonine kinase 1; Involved in the transduction of TNF si [...] (671 aa)
      0.946
ERBB2IP
erbb2 interacting protein; Acts as an adapter for the receptor ERBB2, in epithelia. By binding [...] (1371 aa)
     0.923
TRIM27
tripartite motif-containing 27 (249 aa)
      0.919
NLRC4
NLR family, CARD domain containing 4; Plays a role in the promotion of apoptosis (1024 aa)
    0.915
DIF
Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)( [...] (233 aa)
       0.906
TNF
tumor necrosis factor (TNF superfamily, member 2); Cytokine that binds to TNFRSF1A/TNFR1 and TN [...] (233 aa)
       0.902
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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additional (white) nodes

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