STRING 9.05 
  ABCA3 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3; Plays an important role in the formation of pulmonary surfactant, probably by transporting lipids such as cholesterol (1704 aa)
(Homo sapiens)
Predicted Functional Partners:
ESR1
estrogen receptor 1; Nuclear hormone receptor. The steroid hormones and their receptors are inv [...] (595 aa)
      0.901
NKX2-1
NK2 homeobox 1; Transcription factor that binds and activates the promoter of thyroid specific [...] (401 aa)
       0.877
NFATC3
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3; Plays a role in the [...] (1075 aa)
       0.833
STAT3
signal transducer and activator of transcription 3 (acute-phase response factor); Transcription [...] (770 aa)
       0.809
IL6
interleukin 6 (interferon, beta 2); Cytokine with a wide variety of biological functions. It is [...] (212 aa)
       0.804
SFTPC
surfactant protein C; Pulmonary surfactant associated proteins promote alveolar stability by lo [...] (197 aa)
       0.792
SFTPB
surfactant protein B; Pulmonary surfactant-associated proteins promote alveolar stability by lo [...] (381 aa)
       0.778
LAMP3
lysosomal-associated membrane protein 3; Might change the lysosome function after the transfer [...] (416 aa)
      0.729
CSF2RA
colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage); Low affinit [...] (400 aa)
       0.657
CANX
calnexin; Calcium-binding protein that interacts with newly synthesized glycoproteins in the en [...] (592 aa)
      0.649
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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