STRING 9.05 
  PBK protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
PBK
PDZ binding kinase; Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin-induced DNA damage (322 aa)
(Homo sapiens)
Predicted Functional Partners:
CDK1
cyclin-dependent kinase 1; Plays a key role in the control of the eukaryotic cell cycle. It is [...] (297 aa)
    0.986
CCNB1
cyclin B1; Essential for the control of the cell cycle at the G2/M (mitosis) transition (433 aa)
     0.981
TP53
tumor protein p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apo [...] (393 aa)
      0.973
TTK
TTK protein kinase; Phosphorylates proteins on serine, threonine, and tyrosine. Probably associ [...] (857 aa)
      0.963
NCAPG
non-SMC condensin I complex, subunit G; Regulatory subunit of the condensin complex, a complex [...] (1015 aa)
      0.961
NUF2
NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae); Acts as a component of the [...] (464 aa)
      0.957
NDC80
NDC80 homolog, kinetochore complex component (S. cerevisiae); Acts as a component of the essent [...] (642 aa)
      0.956
NUSAP1
nucleolar and spindle associated protein 1; Microtubule-associated protein with the capacity to [...] (441 aa)
      0.956
CENPF
centromere protein F, 350/400ka (mitosin); Required for kinetochore function and chromosome seg [...] (3114 aa)
      0.954
BUB1
budding uninhibited by benzimidazoles 1 homolog (yeast); Involved in cell cycle checkpoint enfo [...] (1085 aa)
      0.954
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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