STRING 9.05 
  MAP2K1 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
MAP2K1
mitogen-activated protein kinase kinase 1; Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates ERK1 and ERK2 MAP kinases (393 aa)
(Homo sapiens)
Predicted Functional Partners:
MAPK1
mitogen-activated protein kinase 1; Involved in both the initiation and regulation of meiosis, [...] (360 aa)
    0.999
RAF1
v-raf-1 murine leukemia viral oncogene homolog 1; Involved in the transduction of mitogenic sig [...] (648 aa)
    0.999
MAPK3
mitogen-activated protein kinase 3; Involved in both the initiation and regulation of meiosis, [...] (379 aa)
    0.999
BRAF
v-raf murine sarcoma viral oncogene homolog B1; Involved in the transduction of mitogenic signa [...] (766 aa)
    0.997
KSR1
kinase suppressor of ras 1; Location-regulated scaffolding protein connecting MEK to RAF. Promo [...] (846 aa)
     0.995
YWHAB
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide; Adapt [...] (246 aa)
      0.993
ARAF
v-raf murine sarcoma 3611 viral oncogene homolog; Involved in the transduction of mitogenic sig [...] (606 aa)
    0.988
YWHAE
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide; Ad [...] (255 aa)
     0.987
MAP3K1
mitogen-activated protein kinase kinase kinase 1; Component of a protein kinase signal transduc [...] (1512 aa)
    0.985
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide; Adapt [...] (245 aa)
      0.983
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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