STRING 9.05 
  BCR protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
BCR
breakpoint cluster region; GTPase-activating protein for RAC1 and CDC42. Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them. Displays serine/threonine kinase activity (1271 aa)
(Homo sapiens)
Predicted Functional Partners:
GRB2
growth factor receptor-bound protein 2; Adapter protein that provides a critical link between c [...] (217 aa)
     0.999
ABL1
c-abl oncogene 1, receptor tyrosine kinase; Regulates cytoskeleton remodeling during cell diffe [...] (1149 aa)
     0.999
CRKL
v-crk sarcoma virus CT10 oncogene homolog (avian)-like; May mediate the transduction of intrace [...] (303 aa)
     0.998
PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide; 3-phosphorylates the cellular phosphoi [...] (1102 aa)
      0.993
FES
feline sarcoma oncogene (822 aa)
      0.989
PIK3CA
phosphoinositide-3-kinase, catalytic, alpha polypeptide; Phosphorylates PtdIns, PtdIns4P and Pt [...] (1068 aa)
      0.989
SOS1
son of sevenless homolog 1 (Drosophila); Promotes the exchange of Ras-bound GDP by GTP (1333 aa)
     0.987
VAV2
vav 2 guanine nucleotide exchange factor; Guanine nucleotide exchange factor for the Rho family [...] (878 aa)
     0.985
ARHGDIA
Rho GDP dissociation inhibitor (GDI) alpha; Regulates the GDP/GTP exchange reaction of the Rho [...] (204 aa)
      0.981
CBL
Cas-Br-M (murine) ecotropic retroviral transforming sequence; Participates in signal transducti [...] (906 aa)
     0.980
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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additional (white) nodes

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