STRING 9.05 
  IL13 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
IL13
interleukin 13; Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses (146 aa)
(Homo sapiens)
Predicted Functional Partners:
IL13RA1
interleukin 13 receptor, alpha 1; Binds IL13 with a low affinity. Together with IL4R-alpha can [...] (427 aa)
     0.999
IL4R
interleukin 4 receptor; Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1 [...] (825 aa)
     0.999
IL13RA2
interleukin 13 receptor, alpha 2; Binds as a monomer with high affinity to interleukin 13 (IL13 [...] (380 aa)
      0.998
IL4
interleukin 4; Participates in at least several B-cell activation processes as well as of other [...] (153 aa)
      0.992
GATA3
GATA binding protein 3; Transcriptional activator which binds to the enhancer of the T-cell rec [...] (444 aa)
      0.984
TSLP
thymic stromal lymphopoietin; Cytokine that induces the release of T cell-attracting chemokines [...] (159 aa)
      0.971
VCAM1
vascular cell adhesion molecule 1; Important in cell-cell recognition. Appears to function in l [...] (739 aa)
      0.957
IL18
interleukin 18 (interferon-gamma-inducing factor); Augments natural killer cell activity in spl [...] (193 aa)
      0.948
IL5
interleukin 5 (colony-stimulating factor, eosinophil); Factor that induces terminal differentia [...] (134 aa)
      0.947
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced; Carries out a dual f [...] (847 aa)
       0.947
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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