STRING 9.05 
  UMOD protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
UMOD
uromodulin; Not known. May play a role in regulating the circulating activity of cytokines as it binds to IL-1, IL-2 and TNF with high affinity (640 aa)
(Homo sapiens)
Predicted Functional Partners:
HNF1B
HNF1 homeobox B; Transcription factor, probably binds to the inverted palindrome 5'-GTTAATNATTA [...] (557 aa)
       0.899
IGK@
immunoglobulin kappa constant (107 aa)
       0.657
MMP8
matrix metallopeptidase 8 (neutrophil collagenase); Can degrade fibrillar type I, II, and III c [...] (467 aa)
      0.645
IL4R
interleukin 4 receptor; Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1 [...] (825 aa)
       0.627
IFNGR1
interferon gamma receptor 1; Receptor for interferon gamma. Two receptors bind one interferon g [...] (489 aa)
       0.623
LTA
lymphotoxin alpha (TNF superfamily, member 1) (205 aa)
      0.621
ENSG00000226979
Lymphotoxin-alpha Precursor (LT-alpha)(TNF-beta)(Tumor necrosis factor ligand superfamily membe [...] (205 aa)
       0.621
PKHD1
polycystic kidney and hepatic disease 1 (autosomal recessive); May be a receptor protein that a [...] (4074 aa)
       0.619
SH3GL1
SH3-domain GRB2-like 1; Implicated in endocytosis. May recruit other proteins to membranes with [...] (368 aa)
       0.543
MCL1
myeloid cell leukemia sequence 1 (BCL2-related); Involved in the regulation of apoptosis versus [...] (350 aa)
       0.540
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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additional (white) nodes

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