STRING 9.05 
  F2 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
F2
coagulation factor II (thrombin); Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (622 aa)
(Homo sapiens)
Predicted Functional Partners:
SERPINC1
serpin peptidase inhibitor, clade C (antithrombin), member 1; Most important serine protease in [...] (464 aa)
    0.999
THBD
thrombomodulin; Thrombomodulin is a specific endothelial cell receptor that forms a 1-1 stoichi [...] (575 aa)
     0.999
F5
coagulation factor V (proaccelerin, labile factor); Central regulator of hemostasis. It serves [...] (2224 aa)
    0.999
FGA
fibrinogen alpha chain; Fibrinogen has a double function- yielding monomers that polymerize int [...] (866 aa)
    0.999
GP1BA
glycoprotein Ib (platelet), alpha polypeptide; GP-Ib, a surface membrane protein of platelets, [...] (640 aa)
     0.999
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1; Thrombin inhibitor activated [...] (499 aa)
    0.999
F2R
coagulation factor II (thrombin) receptor; High affinity receptor for activated thrombin couple [...] (425 aa)
     0.998
FGB
fibrinogen beta chain; Fibrinogen has a double function- yielding monomers that polymerize into [...] (491 aa)
    0.998
FGG
fibrinogen gamma chain; Fibrinogen has a double function- yielding monomers that polymerize int [...] (453 aa)
    0.998
F8
coagulation factor VIII, procoagulant component; Factor VIII, along with calcium and phospholip [...] (2351 aa)
     0.997
 
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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
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