STRING 9.05 
  PRSS1 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
PRSS1
protease, serine, 2 (trypsin 2); Has activity against the synthetic substrates Boc-Phe- Ser-Arg-Mec, Boc-Leu-Thr-Arg-Mec, Boc-Gln-Ala-Arg-Mec and Boc-Val- Pro-Arg-Mec. The single-chain form is more active than the two- chain form against all of these substrates (247 aa)
(Homo sapiens)
Predicted Functional Partners:
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase); May play [...] (707 aa)
     0.967
DEFA5
defensin, alpha 5, Paneth cell-specific; Has antimicrobial activity against Gram-negative and G [...] (94 aa)
      0.959
MMP3
matrix metallopeptidase 3 (stromelysin 1, progelatinase); Can degrade fibronectin, laminin, gel [...] (477 aa)
      0.919
MMP8
matrix metallopeptidase 8 (neutrophil collagenase); Can degrade fibrillar type I, II, and III c [...] (467 aa)
      0.916
MMP1
matrix metallopeptidase 1 (interstitial collagenase); Cleaves collagens of types I, II, and III [...] (469 aa)
      0.914
MMP7
matrix metallopeptidase 7 (matrilysin, uterine); Degrades casein, gelatins of types I, III, IV, [...] (267 aa)
      0.912
MMP13
matrix metallopeptidase 13 (collagenase 3); Degrades collagen type I. Does not act on gelatin o [...] (471 aa)
      0.912
COL18A1
collagen, type XVIII, alpha 1; COLA18A probably plays a major role in determining the retinal s [...] (1754 aa)
      0.901
MMP10
matrix metallopeptidase 10 (stromelysin 2); Can degrade fibronectin, gelatins of type I, III, I [...] (476 aa)
      0.900
F2RL1
coagulation factor II (thrombin) receptor-like 1; Receptor for trypsin and trypsin-like enzymes [...] (397 aa)
      0.867
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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