STRING 9.05 
  PRKACA protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
PRKACA
protein kinase, cAMP-dependent, catalytic, alpha; Phosphorylates a large number of substrates in the cytoplasm and the nucleus (351 aa)
(Homo sapiens)
Predicted Functional Partners:
BAD
BCL2-associated agonist of cell death; Promotes cell death. Successfully competes for the bindi [...] (168 aa)
      0.967
CFTR
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member [...] (1480 aa)
      0.967
ADCY5
adenylate cyclase 5; This is a membrane-bound, calcium-inhibitable adenylyl cyclase (1261 aa)
      0.959
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) (381 aa)
    0.957
CREB1
cAMP responsive element binding protein 1; This protein binds the cAMP response element (CRE), [...] (341 aa)
     0.930
ITPR1
inositol 1,4,5-triphosphate receptor, type 1; Intracellular channel that mediates calcium relea [...] (2710 aa)
     0.928
GSK3B
glycogen synthase kinase 3 beta; Participates in the Wnt signaling pathway. Implicated in the h [...] (433 aa)
   0.926
HDAC8
histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal p [...] (377 aa)
      0.926
RYR2
ryanodine receptor 2 (cardiac); Communication between transverse-tubules and sarcoplasmic retic [...] (4965 aa)
     0.925
PLN
phospholamban; Phospholamban has been postulated to regulate the activity of the calcium pump o [...] (52 aa)
     0.921
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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