STRING 9.05 
  C10orf2 protein (Homo sapiens) - STRING network view

This is the evidence view. Different line colors represent the types of evidence for the association.

Your Input:
Twinkle protein, mitochondrial Precursor (EC 3.6.1.-)(T7 gp4-like protein with intramitochondrial nucleoid localization)(T7-like mitochondrial DNA helicase)(Progressive external ophthalmoplegia 1 protein); Involved in mitochondrial DNA (mtDNA) metabolism. Could function as an adenine nucleotide-dependent DNA helicase. Function inferred to be critical for lifetime maintenance of mtDNA integrity. In vitro, forms in combination with POLG, a processive replication machinery, which can use double-stranded DNA (dsDNA) as template to synthesize single-stranded DNA (ssDNA) molecules. May be a [...] (684 aa)
(Homo sapiens)
Predicted Functional Partners:
kelch-like 1 (Drosophila); May play a role in organizing the actin cytoskeleton of the brain ce [...] (748 aa)
polymerase (DNA directed), gamma; Involved in the replication of mitochondrial DNA (1239 aa)
STAM binding protein; Zinc metalloprotease that specifically cleaves 'Lys-63'- linked polyubiqu [...] (424 aa)
ubiquitin specific peptidase 8; Hydrolase that can remove conjugated ubiquitin from proteins an [...] (1118 aa)
tachykinin, precursor 1; Tachykinins are active peptides which excite neurons, evoke behavioral [...] (129 aa)
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4; Ca [...] (298 aa)
tocopherol (alpha) transfer protein; Binds alpha-tocopherol and enhances its transfer between s [...] (278 aa)
polymerase (DNA directed), gamma 2, accessory subunit; Mitochondrial polymerase processivity su [...] (485 aa)
family with sequence similarity 178, member A (1186 aa)
ataxin 3; Interacts with key regulators (CBP, p300 and PCAF) of transcription and represses tra [...] (361 aa)
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Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
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Co-expression Experiments Databases Textmining
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