STRING 9.05 
  GAK protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
GAK
cyclin G associated kinase; Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin- coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1 (1311 aa)
(Homo sapiens)
Predicted Functional Partners:
AR
androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that re [...] (920 aa)
      0.850
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha); Sequence-specifi [...] (437 aa)
       0.800
HSPA8
heat shock 70kDa protein 8; Chaperone. Isoform 2 may function as an endogenous inhibitory regul [...] (646 aa)
      0.692
CCNG1
cyclin G1; May play a role in growth regulation. Is associated with G2/M phase arrest in respon [...] (295 aa)
      0.683
AP2M1
adaptor-related protein complex 2, mu 1 subunit; Component of the adaptor protein complex 2 (AP [...] (435 aa)
      0.669
AP1M2
adaptor-related protein complex 1, mu 2 subunit; Subunit of clathrin-associated adaptor protein [...] (423 aa)
      0.660
CDK5
cyclin-dependent kinase 5; Probably involved in the control of the cell cycle. Interacts with D [...] (292 aa)
     0.646
CLTC
clathrin, heavy chain (Hc); Clathrin is the major protein of the polyhedral coat of coated pits [...] (1675 aa)
      0.642
CREBBP
CREB binding protein; Acetylates histones, giving a specific tag for transcriptional activation [...] (2442 aa)
      0.640
AP1M1
adaptor-related protein complex 1, mu 1 subunit; Subunit of clathrin-associated adaptor protein [...] (435 aa)
      0.628
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
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Co-expression Experiments Databases Textmining
 
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