STRING 9.05 
  PRF1 protein (Homo sapiens) - STRING network view

This is the evidence view. Different line colors represent the types of evidence for the association.

Your Input:
perforin 1 (pore forming protein); In the presence of calcium, binds to target cell membranes. Inserts into target cell membranes and forms pores, and so contributes to cytolysis and apoptosis of target cells (555 aa)
(Homo sapiens)
Predicted Functional Partners:
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1); This enzyme is ne [...] (247 aa)
interleukin 2; Produced by T-cells in response to antigenic or mitogenic stimulation, this prot [...] (153 aa)
interleukin 2 receptor, alpha; Receptor for interleukin-2 (272 aa)
CD8a molecule; Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing t [...] (235 aa)
CD247 molecule; Probable role in assembly and expression of the TCR complex as well as signal t [...] (164 aa)
CD3e molecule, epsilon (CD3-TCR complex); The CD3 complex mediates signal transduction (207 aa)
interleukin 2 receptor, beta; Receptor for interleukin-2. This beta subunit is involved in rece [...] (551 aa)
eomesodermin homolog (Xenopus laevis); Functions as a transcriptional activator playing a cruci [...] (686 aa)
CD86 molecule; Receptor involved in the costimulatory signal essential for T-lymphocyte prolife [...] (329 aa)
CD3d molecule, delta (CD3-TCR complex); The CD3 complex mediates signal transduction (171 aa)
   Neighborhood  Fusion  Occurence  Coexpression  Experiments  Database  Textmining      Summary Network


Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
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