STRING 9.05 
  SLC2A2 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
SLC2A2
solute carrier family 2 (facilitated glucose transporter), member 2; Facilitative glucose transporter. This isoform likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney (524 aa)
(Homo sapiens)
Predicted Functional Partners:
INS
insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monos [...] (200 aa)
       0.954
GCG
glucagon; Glicentin may modulate gastric acid secretion and the gastro-pyloro-duodenal activity [...] (180 aa)
       0.953
HNF1A
HNF1 homeobox A; Required for the expression of several liver specific genes. Binds to the inve [...] (631 aa)
      0.951
FOXA2
forkhead box A2; Transcription activator for a number of liver genes such as AFP, albumin, tyro [...] (463 aa)
      0.942
SLC5A1
solute carrier family 5 (sodium/glucose cotransporter), member 1; Actively transports glucose i [...] (664 aa)
      0.933
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5; Cytochalasin B-se [...] (501 aa)
    0.910
LEP
leptin; May function as part of a signaling pathway that acts to regulate the size of the body [...] (167 aa)
       0.900
GCK
glucokinase (hexokinase 4); Catalyzes the initial step in utilization of glucose by the beta-ce [...] (466 aa)
       0.861
PDX1
pancreatic and duodenal homeobox 1; Activates insulin, somatostatin, glucokinase, islet amyloid [...] (283 aa)
      0.844
DIF
Tumor necrosis factor Precursor (TNF-alpha)(Tumor necrosis factor ligand superfamily member 2)( [...] (233 aa)
       0.838
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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