STRING 9.05 
  PDZD3 protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
PDZD3
PDZ domain containing 3; Acts as a regulatory protein that associates with GUCY2C and negatively modulates its heat-stable enterotoxin-mediated activation. Stimulates SLC9A3 activity in the presence of elevated calcium ions (491 aa)
(Homo sapiens)
Predicted Functional Partners:
CFTR
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member [...] (1480 aa)
      0.917
SLC22A3
solute carrier family 22 (extraneuronal monoamine transporter), member 3; Mediates potential-de [...] (556 aa)
      0.916
GUCY2C
guanylate cyclase 2C (heat stable enterotoxin receptor); Receptor for the E.coli heat-stable en [...] (1073 aa)
      0.862
TRPV6
transient receptor potential cation channel, subfamily V, member 6; Calcium selective cation ch [...] (725 aa)
       0.859
SLC34A1
solute carrier family 34 (sodium phosphate), member 1; May be involved in actively transporting [...] (639 aa)
      0.744
SLC22A4
solute carrier family 22 (organic cation/ergothioneine transporter), member 4; Sodium-ion depen [...] (551 aa)
      0.650
ABCC2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2; Mediates hepatobiliary excretion of nu [...] (1545 aa)
      0.648
SLC22A9
solute carrier family 22 (organic anion transporter), member 9 (553 aa)
      0.625
STAR
steroidogenic acute regulatory protein; Plays a key role in steroid hormone synthesis by enhanc [...] (285 aa)
       0.621
SLC15A2
solute carrier family 15 (H+/peptide transporter), member 2; Proton-coupled intake of oligopept [...] (729 aa)
       0.609
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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