STRING 9.05 
  FLNC protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
FLNC
filamin C, gamma; Muscle-specific filamin, which plays a central role in muscle cells, probably by functioning as a large actin-cross- linking protein. May be involved in reorganizing the actin cytoskeleton in response to signaling events, and may also display structural functions at the Z-disks in muscle cells. Critical for normal myogenesis and for maintaining the structural integrity of the muscle fibers (2725 aa)
(Homo sapiens)
Predicted Functional Partners:
MYOT
myotilin; Component of a complex of multiple actin cross-linking proteins. Involved in the cont [...] (498 aa)
      0.980
MYOZ1
myozenin 1; Myozenins may serve as intracellular binding proteins involved in linking Z-disk pr [...] (299 aa)
      0.975
MAP2K4
mitogen-activated protein kinase kinase 4; Dual specificity kinase that activates the JUN kinas [...] (399 aa)
     0.927
FBLIM1
filamin binding LIM protein 1; Serves as an anchoring site for cell-ECM adhesion proteins and f [...] (374 aa)
      0.910
FLNA
filamin A, alpha; Promotes orthogonal branching of actin filaments and links actin filaments to [...] (2647 aa)
     0.901
SGCG
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein); Component of the sarcoglycan com [...] (291 aa)
      0.899
XIRP1
xin actin-binding repeat containing 1; Protects actin filaments from depolymerization (1843 aa)
       0.890
SGCD
sarcoglycan, delta (35kDa dystrophin-associated glycoprotein); Component of the sarcoglycan com [...] (290 aa)
      0.888
MYOZ3
myozenin 3; Myozenins may serve as intracellular binding proteins involved in linking Z-disk pr [...] (251 aa)
      0.879
KY
kyphoscoliosis peptidase; Probable cytoskeleton-associated protease required for normal muscle [...] (661 aa)
      0.861
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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