STRING 9.05 
  CHAT protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
CHAT
choline acetyltransferase; Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses (748 aa)
(Homo sapiens)
Predicted Functional Partners:
SLC18A3
solute carrier family 18 (vesicular acetylcholine), member 3; Involved in acetylcholine transpo [...] (532 aa)
      0.984
NGF
nerve growth factor (beta polypeptide); Nerve growth factor is important for the development an [...] (241 aa)
       0.955
SLC5A7
solute carrier family 5 (choline transporter), member 7; Imports choline from the extracellular [...] (580 aa)
     0.939
KIFAP3
kinesin-associated protein 3; Involved in tethering the chromosomes to the spindle pole and in [...] (792 aa)
       0.930
CHKA
choline kinase alpha; May have a regulatory role in phosphatidylcholine synthesis (457 aa)
      0.929
SYT1
synaptotagmin I; May have a regulatory role in the membrane interactions during trafficking of [...] (422 aa)
      0.911
ACHE
acetylcholinesterase (Yt blood group); Terminates signal transduction at the neuromuscular junc [...] (617 aa)
       0.909
VAMP2
vesicle-associated membrane protein 2 (synaptobrevin 2); Involved in the targeting and/or fusio [...] (116 aa)
      0.906
RAB3A
RAB3A, member RAS oncogene family; Involved in exocytosis by regulating a late step in synaptic [...] (220 aa)
      0.903
PHOSPHO1
phosphatase, orphan 1; Phosphatase that has a high activity toward phosphoethanolamine (PEA) an [...] (292 aa)
       0.899
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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