STRING 9.05 
  ERAS protein (Homo sapiens) - STRING network view
 

This is the evidence view. Different line colors represent the types of evidence for the association.

 
   
Your Input:
ERAS
ES cell expressed Ras; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the tumor-like growth properties of embryonic stem cells (By similarity) (233 aa)
(Homo sapiens)
Predicted Functional Partners:
PIK3CD
phosphoinositide-3-kinase, catalytic, delta polypeptide (1044 aa)
       0.619
PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide; 3-phosphorylates the cellular phosphoi [...] (1102 aa)
       0.619
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha); Binds to activated (phosphorylated) pr [...] (724 aa)
       0.619
RAF1
v-raf-1 murine leukemia viral oncogene homolog 1; Involved in the transduction of mitogenic sig [...] (648 aa)
       0.619
PAX8
paired box 8; Transcription factor for the thyroid-specific expression of the genes exclusively [...] (450 aa)
       0.429
NANOG
Nanog homeobox; Transcription regulator involved in inner cell mass and embryonic stem (ES) cel [...] (305 aa)
       0.429
PTPN11
protein tyrosine phosphatase, non-receptor type 11; Acts downstream of various receptor and cyt [...] (593 aa)
       0.423
KLK3
kallikrein-related peptidase 3; Hydrolyzes semenogelin-1 thus leading to the liquefaction of th [...] (261 aa)
       0.411
LGALS3
lectin, galactoside-binding, soluble, 3; Galactose-specific lectin which binds IgE. May mediate [...] (250 aa)
       0.407
 
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
 
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