STRING 9.05 
  MAPT protein (Homo sapiens) - STRING network view

This is the evidence view. Different line colors represent the types of evidence for the association.

Your Input:
microtubule-associated protein tau; Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N- terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabil [...] (776 aa)
(Homo sapiens)
Predicted Functional Partners:
STIP1 homology and U-box containing protein 1; Modulates the activity of several chaperone comp [...] (303 aa)
glycogen synthase kinase 3 beta; Participates in the Wnt signaling pathway. Implicated in the h [...] (433 aa)
cyclin-dependent kinase 5; Probably involved in the control of the cell cycle. Interacts with D [...] (292 aa)
ubiquitin C (685 aa)
FYN oncogene related to SRC, FGR, YES; Implicated in the control of cell growth. Plays a role i [...] (537 aa)
apolipoprotein E; Mediates the binding, internalization, and catabolism of lipoprotein particle [...] (317 aa)
v-akt murine thymoma viral oncogene homolog 1; General protein kinase capable of phosphorylatin [...] (480 aa)
synuclein, alpha (non A4 component of amyloid precursor); May be involved in the regulation of [...] (140 aa)
heat shock 70kDa protein 4 (840 aa)
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide; Adapt [...] (245 aa)
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Info & Parameters ...
Network Display - Nodes are either colored (if they are directly linked to the input - as in the table) or white (nodes of a higher iteration/depth). Edges, i.e. predicted functional links, consist of up to eight lines: one color for each type of evidence. Hover or click to reveal more information about the node/edge.

Active Prediction Methods:
Neighborhood Gene Fusion Co-occurrence
Co-expression Experiments Databases Textmining
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